Effect of Model Traumatic Injury on Hepatic Drug-metabolizing Enzymes
- 1 October 1980
- journal article
- research article
- Published by Wolters Kluwer Health
- Vol. 20 (10), 884-886
- https://doi.org/10.1097/00005373-198010000-00012
Abstract
Abdominal aorta ligation in rats was a suitable model traumatic injury for the study of effect of trauma on drug-metabolizing enzymes. This procedure resulted in a rapid decrease in cytochrome P-450, and mixed function amine oxidase activities. Recovery of mixed function amine oxidase activity was slower than recovery of cytochrome P-450 activity.This publication has 8 references indexed in Scilit:
- Hepatic dysfunction following trauma: experimental studiesJournal of Surgical Research, 1977
- The mechanism of the effect of acute stress on hexobarbital metabolismToxicology and Applied Pharmacology, 1976
- A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye BindingAnalytical Biochemistry, 1976
- Microsomal Oxidases. II. Properties of a Pork Liver Microsomal N-Oxide Dealkylase*Biochemistry, 1966
- Microsomal Oxidases. I. The Isolation and Dialkylarylamine Oxygenase Activity of Pork Liver Microsomes*Biochemistry, 1966
- CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES .I. EVIDENCE FOR ITS HEMOPROTEIN NATURE1964
- The Biosynthesis of Trimethylamine-N-OxideJournal of Biological Chemistry, 1962
- A QUANTITATIVE METHOD FOR THE PRODUCTION OF EXPERIMENTAL TRAUMATIC SHOCK WITHOUT HÆMORRHAGE IN UNANÆSTHETIZED ANIMALSQuarterly Journal of Experimental Physiology and Cognate Medical Sciences, 1942