The Site of Involvement of Hypertension within the Cochlea:A Comparative Study of Normotensive and Spontaneously Hypertensive Rats
- 1 January 1984
- journal article
- research article
- Published by Taylor & Francis in Acta Oto-Laryngologica
- Vol. 97 (3-4), 257-265
- https://doi.org/10.3109/00016488409130987
Abstract
The function and morphology of the cochlea of the spontaneously hypertensive rat (SHR) were examined and compared with the age-paired normotensive Wistar Kyoto rat (WKY). Electrocochleographic study revealed that the function of the cochlea in the SHR declined with increasing age to a greater extent than that of WKY. EM study revealed that the primary site of the cochlear deterioration of the SHR was the vascular stria, followed by the organ of Corti. Some hypotheses to explain this phenomenon are proposed for further study.This publication has 17 references indexed in Scilit:
- Noise-induced hearing loss in normotensive and spontaneously hypertensive ratsHearing Research, 1982
- Susceptibility of the sympathectomized ear to noise-induced hearing lossActa Physiologica Scandinavica, 1982
- Effect of Ethacrynic Acid, Furosemide, and Ouabain Upon the Endolymphatic Potential and Upon High Energy Phosphates of the Stria VascularisThe Laryngoscope, 1978
- Effect of bumetanide on the positive endocochlear dc potential of the catToxicology and Applied Pharmacology, 1976
- Cardiovascular Risk Factors and Hearing Loss: A Study of 1000 Fifty-Year-Old MenActa Oto-Laryngologica, 1975
- The permeability of blood vessels in the guinea pig cochleaBrain Structure and Function, 1974
- Horseradish Peroxidase in the Lateral Cochlear Wall: An Electron Microscopic Study of TransportJAMA Otolaryngology–Head & Neck Surgery, 1971
- The cochlear potentialsPflügers Archiv - European Journal of Physiology, 1970
- Effect of Ouabain on Cochlear Potentials and Endolymph Composition in Guinea PigsActa Oto-Laryngologica, 1970
- Perceptive Hearing Loss and Arterial HypertensionJAMA Otolaryngology–Head & Neck Surgery, 1968