Integration from proteins to organs: the Physiome Project
Top Cited Papers
- 1 March 2003
- journal article
- review article
- Published by Springer Nature in Nature Reviews Molecular Cell Biology
- Vol. 4 (3), 237-243
- https://doi.org/10.1038/nrm1054
Abstract
The Physiome Project will provide a framework for modelling the human body, using computational methods that incorporate biochemical, biophysical and anatomical information on cells, tissues and organs. The main project goals are to use computational modelling to analyse integrative biological function and to provide a system for hypothesis testing.Keywords
This publication has 32 references indexed in Scilit:
- Computational approaches to cellular rhythmsNature, 2002
- Control, exploitation and tolerance of intracellular noiseNature, 2002
- Modelling and visualising the heartComputing and Visualization in Science, 2002
- Mathematical modelling of the heart: cell to organChaos, Solitons, and Fractals, 2002
- Systems Biology: A Brief OverviewScience, 2002
- Influence of transmural repolarization gradients on the electrophysiology and pharmacology of ventricular myocardium. Cellular basis for the Brugada and long–QT syndromesPhilosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2001
- A short introduction to CellMLPhilosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2001
- The architecture of the heart: a data–based modelPhilosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2001
- A physical map of the human genomeNature, 2001
- Computational modelling of biological systems: tools and visionsPhilosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2000