The clinical entity known since 1894 as Gilchrist's disease or American blastomycosis has usually been thought of as a mycologic entity as well. The subject has been complicated, however, by the incrimination of a number of different fungi as the causes of quite similar lesions. It seems best, as Benham1 has suggested, to reserve the name blastomycosis for lesions caused by the species of fungus described by Gilchrist and named Blastomyces dermatitidis and to apply appropriate names to the other somewhat similar diseases caused by other species of fungi. The latter may be collectively designated as the blastomycosis-like infections. This term will be applied here to the mycotic granulomas in which yeastlike cells are found, whether or not they are characterized by budding. My purpose in this paper is to present these more or less similar diseases as a group and to emphasize their similarity and the importance of