Globus pallidus deep brain stimulation for generalized dystonia: Clinical and PET investigation
- 1 September 1999
- journal article
- case report
- Published by Wolters Kluwer Health in Neurology
- Vol. 53 (4), 871
- https://doi.org/10.1212/wnl.53.4.871
Abstract
Article abstract Bilateral globus pallidus internus (GPi) deep brain stimulation (DBS) in a patient with severe idiopathic generalized dystonia resulted in immediate improvement of all aspects of dystonia. During joystick movement, GPi DBS reduced PET activation bilaterally in the primary motor, lateral premotor, supplementary motor, anterior cingulate, and prefrontal areas and ipsilaterally in the lentiform nucleus. Altering basal ganglia function with GPi DBS reverses the overactivity of certain motor cortical areas present in dystonia.Keywords
This publication has 10 references indexed in Scilit:
- Pallidal stimulation in Parkinson's disease patients with a prior unilateral pallidotomy.Canadian Journal of Neurological Sciences, 1998
- Pallidotomy for generalized dystoniaMovement Disorders, 1998
- Changes in cerebral activity pattern due to subthalamic nucleus or internal pallidum stimulation in Parkinson's diseaseAnnals of Neurology, 1997
- A unified statistical approach for determining significant signals in images of cerebral activationHuman Brain Mapping, 1996
- Motor reorganization in acquired hemidystoniaAnnals of Neurology, 1995
- Overactive prefrontal and underactive motor cortical areas in idiopathic dystoniaAnnals of Neurology, 1995
- Anatomical mapping of functional activation in stereotactic coordinate spaceNeuroImage, 1992
- MRI-PET Correlation in Three Dimensions Using a Volume-of-Interest (VOI) AtlasJournal of Cerebral Blood Flow & Metabolism, 1991
- Validity and reliability of a rating scale for the primary torsion dystoniasNeurology, 1985
- Which elements are excited in electrical stimulation of mammalian central nervous system: A reviewBrain Research, 1975