SUPPRESSION OF PUERPERAL LACTATION BY METERGOLINE
- 1 January 1978
- journal article
- research article
- Vol. 51 (1), 113-115
Abstract
Based on the known stimulatory effect of serotonin on prolactin secretion, a trial of suppression of puerperal lactation by a potent serotonin antagonist, metergoline, was carried out in 30 puerperal women who did not want to nurse. The drug was administered orally at the dose of 4 mg 3 times/day for 5 days to all subjects starting between 24 and 72 h from delivery. Lactation was either prevented or rapidly suppressed in all subjects. Rebound of lactation after the end of treatment was observed in 10% of cases. Metergoline administration was associated with a significant suppression of the plasma prolactin levels.This publication has 4 references indexed in Scilit:
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