Variations in behavioral inhibition following different septal lesions in rats.

Abstract

It was found that lesions which produced extensive damage to the septohippocampal system and the lateral septal nuclei produced evidence of perseverative responding in a position-habit reversal task but did not alter passive avoidance. Male albino Holtzman rats served as Ss in 2 experiments. Lesions restricted primarily to the lateral septal nuclei impaired passive avoidance but had little effect on the reversal of a position habit. Damage restricted to either the medial or lateral nuclei enhanced the acquisition of active-avoidance responses in a shuttle box. (19 ref.) (PsycINFO Database Record (c) 2006 APA, all rights reserved)