Surgery of ventricular septal defect and pulmonary vascular resistance
Open Access
- 1 November 1970
- Vol. 25 (6), 665-668
- https://doi.org/10.1136/thx.25.6.665
Abstract
In a series of 65 patients operated upon for ventricular septal defects (VSD), no mortality was attributed to pre-operative raised pulmonary vascular resistance. Eight patients with a severe degree of pulmonary vascular resistance made a full recovery after surgical closure of the ventricular septal defect. Three patients were cyanotic at the time of operation. Mortality in the series was the result of inadequate perfusion during operation, haemorrhage, cardiac tamponade, mediastinal infection, complete heart block or the development of post-operative aortic incompetence. Raised pulmonary vascular resistance and clinical evidence of a dominant left-to-right shunt in the absence of serious intracardiac anatomical complications does not contraindicate surgery for the repair of VSD.Keywords
This publication has 10 references indexed in Scilit:
- Effects of surgical closure of ventricular septal defects upon pulmonary vascular disease.Heart, 1969
- Natural History of Congenital Heart DiseaseCirculation, 1968
- Role of hypoxia in determining pulmonary vascular resistance in infants with ventricular septal defectsThe American Journal of Cardiology, 1967
- Results of repair of ventricular septal defectThe Journal of Thoracic and Cardiovascular Surgery, 1966
- Pulmonary Artery BandingCirculation, 1965
- The Pulmonary Arterial Tree in Ventricular Septal DefectCirculation, 1961
- Relation between Structural Changes in the Small Pulmonary Arteries and the Immediate Reversibility of Pulmonary Hypertension Following Closure of Ventricular and Atrial Septal DefectsCirculation, 1958
- The Pathology of Hypertensive Pulmonary Vascular DiseaseCirculation, 1958
- The Lewis A. Conner Memorial LectureCirculation, 1957
- The treatment of certain congenital malformations of the heart by the creation of pulmonic stenosis to reduce pulmonary hypertension and excessive pulmonary blood flow; a preliminary report.1952