Pituitary Gonadotropin-Releasing Hormone Receptors During the Rat Estrous Cycle
- 22 August 1980
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 209 (4459), 942-944
- https://doi.org/10.1126/science.6250218
Abstract
The binding of [6-alanine]gonadotropin-releasing hormone to pituitary plasma membranes increased threefold between metestrus and early proestrus in female rats. Receptor numbers fell rapidly on the afternoon of proestrus coincident with the preovulatory gonadotropin surge. The numbers of receptors for gonadotropin-releasing hormone were positively correlated with concentrations of estradiol in serum; this pattern may be a necessary component of increased pituitary sensitivty to gonadotropin-releasing hormone observed during proestrus.Keywords
This publication has 24 references indexed in Scilit:
- Receptors under pressure. An update on baroreceptors.Circulation Research, 1980
- Hormonal regulation of peptide receptors and target cell responsesNature, 1979
- Measurement of Serum Steroid and Gonadotropin Levels and Uterine and Ovarian Variables throughout 4 Day and 5 Day Estrous Cycles in the Rat1Biology of Reproduction, 1979
- EFFECTS OF GONADAL STEROIDS ON OUTPUT OF LUTEINIZING HORMONE RELEASING FACTOR INTO PITUITARY STALK BLOOD IN THE FEMALE RATJournal of Endocrinology, 1979
- Evidence for ovarian “inhibin”: Suppression of the secondary rise in serum follicle stimulating hormone levels in proestrous rats by injection of porcine follicular fluidProceedings of the National Academy of Sciences, 1977
- Gonadotropin-releasing hormone surge in pro-oestrous ratsNature, 1976
- The use of bacitracin as an inhibitor of the degradation of thyrotropin releasing factor and luteinizing hormone releasing factorBiochemical and Biophysical Research Communications, 1976
- Enzymic degradation of luteinizing hormone-releasing hormone (LH-RH) by hypothalamic tissueBiochemical and Biophysical Research Communications, 1974
- THE ROLE OF SEX STEROID HORMONES IN MODULATING THE RESPONSIVENESS OF THE ANTERIOR PITUITARY GLAND TO LUTEINIZING HORMONE RELEASING FACTOR IN THE FEMALE RATJournal of Endocrinology, 1974
- THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONSAnnals of the New York Academy of Sciences, 1949