Effect of 1,25-dihydroxycholecalciferol on adenosine 3′,5′-cyclic monophosphate production in calvaria of mice
- 1 December 1978
- journal article
- research article
- Published by Springer Nature in Calcified Tissue International
- Vol. 25 (1), 223-225
- https://doi.org/10.1007/bf02010773
Abstract
1,25-dihydroxycholecalciferol (1,25-(OH)2D3), added at doses which stimulate bone resorption in the system used, did not increase adenosine 3′,5′-cyclic monophosphate (cAMP) production in vitro in mouse calvaria incubated for up to 48 h. Thus 1,25-(OH)2D3 does not appear to stimulate bone resorption through involvement of an increased cAMP production.Keywords
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