THE RELATIONSHIP OF THE EXTRINSIC RENAL NERVES TO THE ORIGIN OF EXPERIMENTAL HYPERTENSION

Abstract

The production of arterial hypertension in dogs by constricting the renal arteries, or by irradiation of the kidneys with x-ray, was not affected by preliminary stripping of the renal pedicle of its extrinsic nerve supply. Hence these nerves do not appear to participate in the genesis of renal hypertension. Hypertension produced by constriction of the renal arteries did not result in significant changes in the proteins or lipids of the plasma. The Hb content of the blood was slightly elevated. Renal efficiency, as measured by the content of urea in the blood, was not markedly altered, and bore no relation to the height of the blood pressure, as Goldblatt, Lynch, Hanzal and Summerville have already found.