Evaluation of Tubeless Gastric Analysis

Abstract

IN 1950 Segal and his associates¹ introduced a method for determining free gastric hydrochloric acid based on release of quininium cation from a synthetic ion-exchange resin by the hydrogen ion in gastric secretion. The resin granules were given orally, in a dosage of 2 gm. Two-hourly urine samples were then analyzed for quinine, the presence of quinine in appreciable concentration indicating free gastric hydrochloric acid. Later, Segal et al.² described the procedure in greater detail, reporting results in 106 patients. The test was found to have a high degree of accuracy when compared with gastric analyses conducted previously on samples . . .