Glyoxal and Related Compounds as Potential Blood Sterilizing Agents

Abstract

The comparative virucidal activities of several chemicals were determined. Glyoxal and Kethoxal ([beta]-ethoxy-o-ketobutyraldehyde) were the most potent virucidal agents tested. Electrophoretic measurements indicated that neither chemical was toxic for plasma proteins. Glyoxal was less lytic for human erythro-cytes than was Kethoxal. The experiments indicated that glyoxal may be of potential value in the sterilization of human blood and plasma.