PROGNOSTIC VALUE OF THYROTROPIN- RELEASING HORMONE STIMULATION TEST IN ENDOGENOUS DEPRESSION
- 1 September 1975
- journal article
- Published by Wiley in Acta Psychiatrica Scandinavica
- Vol. 52 (3), 170-177
- https://doi.org/10.1111/j.1600-0447.1975.tb00034.x
Abstract
Thyrotropin-releasing hormone (TRH) stimulation tests were performed in 19 patients with endogenous depression before treatment and when they had apparently recovered following antidepressive treatment. An increase in the maximal serum thyrotropin (TSH) response to TRH of more than 2.0 muU/ml was found in all of ten patients who did not relapse, while such an increase was found in only one of nine patients who did relapse within 6 months. I. e., a correct prognosis was possible in 94.7% (95% confidence limits 74.0 - 99.9%). Through significant changes were found in serum thyroxin (T4), free T4 index, serum triiodothyronine (T3) and free T3 index, these findings were of no prognostic value.Keywords
This publication has 14 references indexed in Scilit:
- EFFECT OF SEVERE, CHRONIC ILLNESS ON THYROID FUNCTIONThe Lancet, 1974
- THYROTROPIN-RELEASING HORMONE AND DEPRESSIONThe Lancet, 1974
- Alterations in Circulating Thyroid Hormones and Thyrotropin in Hepatic Cirrhosis: Evidence for Euthyroidism Despite Subnormal Serum TriiodothyronineJournal of Clinical Endocrinology & Metabolism, 1974
- THYROTROPHIN-RELEASING HORMONE IN THE TREATMENT OF DEPRESSIONThe Lancet, 1974
- EFFECTS OF THYROTROPIN-RELEASING HORMONE IN DEPRESSION*1The Lancet, 1972
- IMPROVEMENT IN MENTAL DEPRESSION WITH DECREASED THYROTROPIN RESPONSE AFTER ADMINISTRATION OF THYROTROPIN-RELEASING HORMONEThe Lancet, 1972
- Thyroid Function and the Response to Liothyronine in DepressionArchives of General Psychiatry, 1972
- PITUITARY-ADRENAL FUNCTION IN SEVERE DEPRESSIVE ILLNESSThe Lancet, 1968
- Plasma cortisol in depressive illnessJournal of Psychiatric Research, 1962
- Depressive Affect and Endocrine FunctionsA.M.A. Archives of Neurology & Psychiatry, 1957