HYPERLIPEMIA IN EARLY STAGES OF ACUTE GLOMERULAR NEPHRITIS*

Abstract

In 111 children suffering from acute glomerular nephritis, serum protein, albumin, cholesterol and total lipid values were obtained during early stages of the disease. These were compared with corresponding values obtained in 123 controls of similar age. Lower values for serum protein and albumin concentration than any obtained in the controls were noted in 20% of the nephritic group. In these, hypoproteinemia and albuminemia were most marked 2-15 days after onset and persisted for as long as 23 days. Higher values for serum cholesterol and total lipid concentration than any obtained in the control group were noted in 40% and 43%, respectively, of the children with acute glomerular nephritis. This mild to moderately severe hyperlipemia may be observed as early as 2-4 days after onset and the highest values were obtained 1-3 weeks after first symptoms of the disease had been noted.