STUDIES ON THE ORIGIN OF BACTERIAL VIRUSES
Open Access
- 20 November 1958
- journal article
- research article
- Published by Rockefeller University Press in The Journal of general physiology
- Vol. 42 (2), 329-334
- https://doi.org/10.1085/jgp.42.2.329
Abstract
The growth rates, the mutation frequency rate constants of the terramycin-resistant cells, the burst size of the phage-producing cells, and the ratio of phage to cells all have a temperature coefficient of about 2 from 20 to 35° (µ = 9 x 103 calories), with a maximum at 40°. The mutation frequency rate constant (or time rate constant) of the phage-producing cells increases from 20 to 45° with a temperature coefficient of about 3 (µ = 2 to 3 x 104 cal.). The change in the values for the growth rate, mutation rate, and cell volume occurs in less than 1 hour, after the temperature is changed. The value for the burst size of phage-producing cells changes for 3 to 4 hours. Prolonged growth of megatherium 899 at 48 to 50° results in the production of C + S phage, in place of T. Returning the culture to 25° results in the production of small T phage.Keywords
This publication has 5 references indexed in Scilit:
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- THE PROPORTION OF TERRAMYCIN-RESISTANT MUTANTS IN B. MEGATHERIUM CULTURESThe Journal of general physiology, 1957
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