Relation of Pantothenic Acid to White Blood Cell Response of Rats Following Stress.
- 1 July 1949
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 71 (3), 368-371
- https://doi.org/10.3181/00379727-71-17194
Abstract
Summary The responses of white blood cells and lymphocytes following swimming and following ACTH were compared in rats on a complete diet, in rats on a pantothenic acid deficient diet, and following swimming only in rats recovering from a period of pantothenic acid deficiency. A typical lymphopenia occurred 2 hours after either swimming or ACTH in rats on the complete diet. This response was partially abolished following either swimming or ACTH in the rats on the pantothenate deficient diet. In rats recovering from pantothenate deficiency, there was an increase in lymphocytes 2 hours after swimming followed by a decrease at 4 hours. These results are interpreted as a reflection of the changes in the adrenal cortex induced by pantothenic acid deficiency.Keywords
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