IMMUNOLOGICAL IN VITRO PARAMETERS IN PATIENTS WITH MULTIPLE SCLEROSIS AND IN NORMAL INDIVIDUALS

Abstract
The general immunological capacity of 40 patients with multiple sclerosis was evaluated with the lymphocyte transformation test including mitogens (PHA [phytohemagglutinin] and PWM [pokeweed mitogen]) and antigens (PPD [purified protein derivative], Candida albicans, Staphylococcus aureus and Escherichia coli). Determination of T [thymus-derived] and B [bone marrow-derived] cells was performed by E [sheep erythrocyte]-, EAC [human erythrocyte, antibody, complement] rosetting and immunofluorescence for surface immunoglobulins. Compared with the results obtained in 42 normal, individuals only minor differences were found.