Action of Purified Gonadotropins on Corpora Lutea in the Cyclic Mouse.

Abstract

Summary The life of hyperemic (functional) corpora lutea in intraocular ovarian transplants in castrated female mice was between one and two days. It was not affected by administration of 0.1 mg of FSH or of LH every 12 hours. It was extended to approximately 5, 8 and 7 days, respectively, by 0.025, 0.1, or 0.2 mg of LTH and to 17 days by 0.1 mg of LH with 0.1 mg of LTH. Deciduomata occurred in response to uterine trauma in animals receiving 0.1 mg LTH, or 0.1 mg LH and LTH, but not in those receiving 0.025 mg LTH or 0.1 mg LH.