Transformation by Rous Sarcoma Virus: A Requirement for DNA Synthesis
- 13 August 1965
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 149 (3685), 757-758
- https://doi.org/10.1126/science.149.3685.757
Abstract
Transient inhibition of DNA synthesis immediately after infection of cells with Rous sarcoma virus prevents subsequent morphological transformationof the cells. Inhibition of DNA synthesis for an identical period before infection, or later in the course of infection, has only slight effect on transformation. Thus DNA synthesis is a specific requirement in the transformation of cells by Rous sarcoma virus.Keywords
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- The role of deoxyribonucleic acid in the synthesis of Rous sarcoma virusVirology, 1964
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- The properties of Rous sarcoma virus purified by density gradient centrifugationVirology, 1961