Prognosis of symptoms in patients with diagnosed chronic organic solvent Intoxication
- 1 November 1982
- journal article
- research article
- Published by Springer Nature in Internationales Archiv für Arbeitsmedizin
- Vol. 51 (1), 81-89
- https://doi.org/10.1007/bf00378413
Abstract
The profile and prognosis of symptoms of 87 patients (mean age 38.6 years) in whom a chronic organic solvent intoxication due to tri- or perchloroethylene or mixtures of solvents had been diagnosed 3–9 years earlier were examined by means of an interview. Both at the time of diagnosis and upon reexamination, the most common symptoms were abnormal fatigue, memory disturbances and headache. Also dizziness, sleep disturbances, sensory symptoms in the extremities, mental depression, concentration difficulties, psychic irritability, emotional lability, tremor and nausea were present in over 60% of patients at the time of diagnosis. Upon reexamination, 52% of the intoxication patients with no other contributing neurological disease felt that their overall subjective condition was better than at the time of diagnosis, 21% felt that it was worse, and 27% reported no change. Most of the individual symptoms had more often changed for the better than for the worse; the differences were statistically significant with regard to abnormal fatigue, headache, dizziness, sleep disturbances, nausea, and emotional lability, whereas memory disturbances had changed in the opposite direction. Younger persons, who had had a longer follow-up period and without regular check-ups at the Institute of Occupational Health seemed to have better prognosis at the group level. Due to the great variation between the individuals, the prognosis was, however, impossible to predict in individual cases.Keywords
This publication has 15 references indexed in Scilit:
- Overall prognosis of patients with diagnosed chronic organic solvent intoxicationInternationales Archiv für Arbeitsmedizin, 1982
- Clinical prognosis of patients with diagnosed chronic solvent intoxicationActa Neurologica Scandinavica, 1982
- Subclinical Neuropathy Associated With Chronic Obstructive Pulmonary DiseaseArchives of Neurology, 1981
- Neurological picture of organic solvent poisoning in industryInternationales Archiv für Arbeitsmedizin, 1980
- Multifocal Nervous System Damage from Inhalation of Volatile HydrocarbonsJournal of Occupational and Environmental Medicine, 1977
- Toxic polyneuropathy of shoe-industry workers. A study of 122 cases.Journal of Neurology, Neurosurgery & Psychiatry, 1976
- Polyneuropathy caused by petroleum benzineInternationales Archiv für Arbeitsmedizin, 1975
- Toxic Polyneuropathy Due to Methyl n-Butyl KetoneArchives of Neurology, 1975
- N-Hexane NeuropathyNew England Journal of Medicine, 1971
- CASE REPORTSAmerican Journal of Psychiatry, 1961