Hemagglutination with Herpes Simplex Virus

Abstract
Herpes simplex virus, which by the usual technique of hemagglutination is inactive, has been shown to produce hemagglutination in the presence of specific immune serum. This virus was adsorbed onto sheep erythrocytes which had been treated with tannic acid. These tannic acid-virus treated cells agglutinated in the presence of specific immune serum. The amount of virus used in the adsorption process had a direct effect upon the hemagglutination titers of the sera. The preparation of reagents and the procedures are described.