Effect of sympathectomy on cardiac UDPG-glycogen transferase activity in the cat

Abstract

The effect of chronic surgical sympathectomy on UDPglucose-glycogen transferase activity of cat heart was studied. Sympathectomy increased the cardiac glycogen concentration and decreased the percent of glycogen transferase in the independent ("I") form. Glycogen phosphorylase activities were not significantly altered. A reciprocal relationship was observed between the percent of transferase I and the myocardial glycogen concentration in hearts of control and sympathectomized cats. Changes in glycogen transferase activity fail to explain the increase in cardiac glycogen which follows cardiac sympathectomy.