Geometrically Mediated Breakup of Drops in Microfluidic Devices
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- 6 February 2004
- journal article
- research article
- Published by American Physical Society (APS) in Physical Review Letters
- Vol. 92 (5), 054503
- https://doi.org/10.1103/physrevlett.92.054503
Abstract
Microfluidic technology offers capabilities for the precise handling of small fluid volumes dispersed as droplets. To fully exploit this potential requires simultaneous generation of multiple size droplets. We demonstrate two methods for passively breaking larger drops into precisely controlled daughter drops using pressure-driven flow in simple microfluidic configurations: (i) a T junction and (ii) flow past isolated obstacles. We quantify conditions for breakup at a T junction and illustrate sequential breakup at T junctions for making small drops at high dispersed phase volume fractions.Keywords
This publication has 15 references indexed in Scilit:
- Phase switching of ordered arrays of liquid crystal emulsionsApplied Physics Letters, 2003
- Formation of dispersions using “flow focusing” in microchannelsApplied Physics Letters, 2003
- Interfacial Tension Driven Monodispersed Droplet Formation from Microfabricated Channel ArrayLangmuir, 2001
- Dynamic Pattern Formation in a Vesicle-Generating Microfluidic DevicePhysical Review Letters, 2001
- Monodisperse Emulsion Generation via Drop Break Off in a Coflowing StreamLangmuir, 1999
- An Integrated Nanoliter DNA Analysis DeviceScience, 1998
- Generation of Steady Liquid Microthreads and Micron-Sized Monodisperse Sprays in Gas StreamsPhysical Review Letters, 1998
- Ordered macroporous materials by emulsion templatingNature, 1997
- Emulsification in Viscoelastic MediaPhysical Review Letters, 1996
- Depletion interactions and fractionated crystallization for polydisperse emulsion purificationJournal of Colloid and Interface Science, 1991