Deoxyribonucleic acid initiation mutation dnaB252 is suppressed by elevated dnaC+ gene dosage
- 1 April 1981
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 146 (1), 418-421
- https://doi.org/10.1128/jb.146.1.418-421.1981
Abstract
The Escherichia coli dnaB252 allele is the only dnaB mutation which confers a DNA initiation-defective phenotype on the cell. The presence of a multicopy hybrid plasmid containing the dnaC+ gene in a dnaB252 strain completely suppressed the temperature-sensitive phenotype. At high temperature, the dnaB252 protein evidently has a lowered affinity for dnaC protein. The formation of a dnaB-dnaC complex is apparently mandatory for initiation.This publication has 20 references indexed in Scilit:
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