Studies on an East African strain of Plasmodium falciparum*1

Abstract

An East African strain of P. falciparum obtained from a child in Kampala, Uganda, was responsive to all anti-malarials tested. Chloroquine 0.45 g, base and quinine 2.5 g base given over 5 days, each produced radical cure. A review of responsiveness of strains of P. falciparum used for infection of volunteers is presented. The data on the response of P. falciparum strains from different world areas indicate that sensitivity to chloroquine and quinine are closely related.