The effect of three frequently applied antibiotics on the colonization resistance of the digestive tract of mice
- 31 May 1979
- journal article
- research article
- Published by Cambridge University Press (CUP) in Epidemiology and Infection
- Vol. 82 (3), 397-405
- https://doi.org/10.1017/s0022172400053924
Abstract
SUMMARY: The influence of treatment with increasing oral doses of three absorbable antibiotics on the colonization resistance of the digestive tract was investigated in mice. Mice treated with ampicillin or epicillin in any of the applied doses had a strongly decreased colonization resistance as demonstrated by ‘bacterial over-growth’ after contamination with resistant strains ofEscherichia coli. After a treatment period of 2 weeks,Streptococcus faecalisbecame resistant in a number of animals. Oral treatment with cephradine on the other hand had no obvious influence on the endogenous flora of the mice, nor was the colonization resistance decreased.This publication has 29 references indexed in Scilit:
- Hands as route of transmission for Klebsiella species.BMJ, 1977
- The Effect of Tetracycline upon Establishment of Escherichia coli of Bovine Origin in the Enteric Tract of ManJournal of Applied Bacteriology, 1974
- DRUG-ASSOCIATED DIARRHŒA AS A POTENTIAL RESERVOIR FOR HOSPITAL' INFECTIONSThe Lancet, 1974
- Determination of the colonization resistance of the digestive tract of individual miceEpidemiology and Infection, 1974
- FLOWER VASES IN HOSPITALS AS RESERVOIRS OF PATHOGENSThe Lancet, 1973
- Sources of contamination of cooked, ready-to-eat cured and uncured meatsEpidemiology and Infection, 1973
- Colonization resistance of the digestive tract of mice during systemic antibiotic treatmentEpidemiology and Infection, 1972
- FACTORS INFLUENCING COLONISATION AND ANTIBIOTIC-RESISTANCE PATTERNS OF GRAM-NEGATIVE BACTERIA IN HOSPITAL PATIENTSThe Lancet, 1972
- Colonization resistance of the digestive tract in conventional and antibiotic-treated miceEpidemiology and Infection, 1971
- Cultural and Biochemical Characteristics of the Genus ChromobacteriumJournal of General Microbiology, 1956