Does Random X-Inactivation in Mammals Reflect a Random Choice Between Two X Chromosomes?
Open Access
- 1 July 2004
- journal article
- editorial
- Published by Oxford University Press (OUP) in Genetics
- Vol. 167 (3), 1525-1528
- https://doi.org/10.1534/genetics.104.029819
Abstract
Inactivation of the maternal or paternal X chromosome in a mammalian embryonic XX cell is believed to involve random choice between the two X's. We propose two alternative models. One suggests that choice is not random, while the other is consistent with random choice, but not one between two X's.Keywords
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