Mechanism of Action of Acetaminophen: Is There a Cyclooxygenase 3?
Open Access
- 1 October 2000
- journal article
- review article
- Published by Oxford University Press (OUP) in Clinical Infectious Diseases
- Vol. 31 (Supplement), S202-S210
- https://doi.org/10.1086/317520
Abstract
Acetaminophen, also known as paracetamol, is a nonsteroidal anti-inflammatory drug with potent antipyretic and analgesic actions but with very weak aKeywords
This publication has 76 references indexed in Scilit:
- Cytokine-to-brain communication: A review & analysis of alternative mechanismsLife Sciences, 1995
- Evaluation of the Antipyretic Effect of Ketorolac, Acetaminophen, and Placebo in Endotoxin‐Induced FeverThe Journal of Clinical Pharmacology, 1994
- Primary structure of sheep prostaglandin endoperoxide synthase deduced from cDNA sequenceFEBS Letters, 1988
- Pharmacology of free radicals; Recent views on their relation to inflammatory mechanismsLife Sciences, 1984
- Effects of 24 hours of aspirin, Bufferin, paracetamol and placebo on normal human gastroduodenal mucosa.Gut, 1982
- Inhibitory actions of desacetylation products of phenacetin and paracetamol on prostaglandin synthetases in neuronal and glial cell lines and rat renal medullaLife Sciences, 1982
- Distribution of prostaglandins in gastric and duodenal mucosa of healthy subjects and duodenal ulcer patients: effects of aspirin and paracetamol.Gut, 1981
- On the synthesis of prostaglandins by human gastric mucosa and its modification by drugsBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1977
- Inhibition of Prostaglandin Synthetase in Brain explains the Anti-pyretic Activity of Paracetamol (4-Acetamidophenol)Nature, 1972
- EFFECT OF ANTI-INFLAMMATORY AGENTS ON PLATELETSThe Lancet, 1968