Difficulties in stratifying neuropathic pain by mechanisms
- 1 August 2003
- journal article
- review article
- Published by Wiley in European journal of pain
- Vol. 7 (4), 353-357
- https://doi.org/10.1016/s1090-3801(03)00051-x
Abstract
The paper addresses issues related to the clinical relevance of currently employed animal models of neuropathic pain and our inability to translate clinical symptoms and signs into pathophysiological mechanisms. A machanism‐based classification of pain is therefore currently not feasible. Suggestions on how to facilitate progress within this area are put forward.Keywords
This publication has 18 references indexed in Scilit:
- Postherpetic Neuralgia: Irritable Nociceptors and DeafferentationNeurobiology of Disease, 1998
- Towards a mechanism-based classification of pain?Pain, 1998
- The effects of mexiletine, desipramine and fluoxetine in rat models involving central sensitizationPain, 1997
- Neuropathic pain sensations are differentially sensitive to dextrorphanNeuroReport, 1994
- When is “pain” appropriate?Pain, 1993
- Mechanical hyperalgesias in neuropathic pain patients: Dynamic and static subtypesAnnals of Neurology, 1993
- Dynamic and static components of mechanical hyperalgesia in human hairy skinPain, 1992
- An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the ratPain, 1992
- Central post-stroke pain — neurological symptoms and pain characteristicsPain, 1989
- A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in manPain, 1988