Methadone Dose and Human Sexual Behavior

Abstract
Among 31 male and 17 female former addicts in methadone maintenance or drug-free treatment, the frequency of sexual behaviors was determined by questionnaires administered at least weekly over several wk. Daily methadone dose (mg/kg) correlated significantly with frequency of genital contacts and orgasms among females, and with frequency of ejaculation among males. The study was open and nonblind, suggested that higher doses of methadone may suppress human sexual behavior.