Cardiac Alkaline and Acid Phosphatase Activity and Potassium Concentration in Dogs with Acute Myocardial Infarction

Abstract

Acid (Acp) and alkaline (Alp) phosphatase activity and potassium (K) concentration were evaluated in infarcted cardiac muscle from dogs between 2 hr and seven days following acute coronary occlusion. Acp increased during the first four days after which the enzyme decreased moderately in both the infarcted and non-infarcted areas. Alp and K were depressed to their lowest concentration at day 3 in the anoxic muscle, while a recovery period was noted from days 4–7.