The inhibition by γ-irradiation of incorporation of 32P into rat thymocytes in vitro
- 1 March 1958
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 68 (3), 410-416
- https://doi.org/10.1042/bj0680410
Abstract
A medium was found in which a large proportion of a respiring suspension of thymic cells retain their normal appearance, as judged by phase-contrast microscopy, for periods up to 2 hours. Uptake of P32 into the deoxyribonucleic acid of the respiring thymocytes was inhibited by 600-950 r of gamma-irradiation. There was an increase in the specific activity of adenosine triphosphate in the irradiated suspensions. Incorporation of P32 into ribonucleic acid was unaffected in vitro.Keywords
This publication has 21 references indexed in Scilit:
- On the Mechanism of Radiation Effect on DNA SynthesisRadiation Research, 1958
- The Effects of Radiationin vitroon Oxidative Phosphorylation and Adenosine TriphosphataseThe British Journal of Radiology, 1955
- Incorporation of P32 into trichloroacetic acid fractions of liver from irradiated and nonirradiated miceArchives of Biochemistry and Biophysics, 1954
- The Concentration of Oxygen Dissolved in Tissues at the Time of Irradiation as a Factor in RadiotherapyThe British Journal of Radiology, 1953
- Some reactions of adenosine and inosine phosphates in animal tissuesBiochimica et Biophysica Acta, 1953
- Factors affecting the incorporation of radioactive phosphate into the pentosenucleic acids of brain slicesBiochemical Journal, 1953
- Incorporation of radioactive phosphate into the nucleic acids of brain slicesBiochemical Journal, 1953
- The sensitivity of lymphocytes to ionising radiationThe Journal of Pathology and Bacteriology, 1952
- Firefly luminescence in the study of energy transfer mechanisms. I. Substrate and enzyme determinationArchives of Biochemistry and Biophysics, 1952
- The effect of X-rays on enzymesBiochemical Journal, 1940