Acute Glomerulonephritis Associated With Normal Serum B1C-Globulin
- 1 January 1968
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Pediatrics & Adolescent Medicine
- Vol. 115 (1), 29-36
- https://doi.org/10.1001/archpedi.1968.02100010031006
Abstract
THE association of acute glomerulonephritis with a previous streptococcal infection is well known.1-6 A reduction of serum hemolytic complement in various forms of nephritis has been adequately documented.7-15 Measurement of serum β1C-globulin levels have directly paralleled the serum hemolytic complement activity and, therefore, the serum β1C-globulin level may be used as an indication of the serum complement activity.11 There exists a preponderance of evidence which indicates that β1C-globulin levels are low in acute glomerulonephritis, and exceptions to this established fact have been noted only in rare instances.12,13 This report will present pertinent clinical, pathologic, and immunologic data in a group of children observed, during the winter months from 1962 to 1963 in the greater Washington, DC area,14 to have acute glomerulonephritis and in which a significant number failed to show a low β1C-globulin level. Methods and Clinical Material Twenty-five children with the clinical features of acute glomerulonephritis, hospitalized on theThis publication has 10 references indexed in Scilit:
- Beta-1C-Globulin: Metabolism in GlomerulonephritisScience, 1966
- Acute poststreptococcal glomerulonephritis: immune deposit disease.JCI Insight, 1966
- The Beta1c Globulin in Childhood Nephrotic SyndromeNew England Journal of Medicine, 1965
- DIAGNOSTIC VALUE OF SERUM COMPLEMENT DETERMINATION IN HEREDITARY GLOMERULONEPHRITIS1965
- Serum Levels of Beta1C Globulin, a Complement Component, in the Nephritides, Lipoid Nephrosis, and Other Conditions *JCI Insight, 1964
- STUDIES OF POSTSTREPTOCOCCAL NEPHRITIS AND OTHER GLOMERULAR DISEASESAnnals of Internal Medicine, 1959
- SERUM COMPLEMENT IN CHILDREN WITH COLLAGEN DISEASES1953
- THE SERUM ANTISTREPTOLYSIN TITER IN ACUTE GLOMERULONEPHRITISJCI Insight, 1938
- STUDIES OF THE VARIATIONS IN THE ANTISTREPTOLYSIN TITER OF THE BLOOD SERUM FROM PATIENTS WITH HEMORRHAGIC NEPHRITIS. I. CONTROL OBSERVATIONS ON HEALTHY INDIVIDUALS AND PATIENTS SUFFERING FROM DISEASES OTHER THAN STREPTOCOCCAL INFECTIONSJCI Insight, 1936
- STUDIES OF THE VARIATIONS IN THE ANTISTREPTOLYSIN TITER OF THE BLOOD SERUM FROM PATIENTS WITH HEMORRHAGIC NEPHRITIS. II. OBSERVATIONS ON PATIENTS SUFFERING FROM STREPTOCOCCAL INFECTIONS, RHEUMATIC FEVER AND ACUTE AND CHRONIC HEMORRHAGIC NEPHRITISJCI Insight, 1936