Predictors of mortality in Gambian children with severe malaria anaemia
- 1 December 1997
- journal article
- other
- Published by Taylor & Francis in Paediatrics and International Child Health
- Vol. 17 (4), 355-359
- https://doi.org/10.1080/02724936.1997.11747910
Abstract
Severe malaria anaemia is a frequent cause of admission to hospital in tropical Africa and about 10% of children with this condition die. To determine ways in which mortality might be reduced we have studied risk factors for a fatal outcome in 173 children with severe malaria anaemia who were assigned to receive blood transfusion because they had a packed cell volume of less than 12% and/or signs of respiratory distress. Twenty-three children died (13%); in 15 cases (65%) death occurred before blood transfusion was given. The presence of respiratory distress was found to be the most important predictor of death. Children with severe malaria anaemia and signs of respiratory distress must therefore be transfused as soon as possible.Keywords
This publication has 9 references indexed in Scilit:
- The pathogenesis of severe malaria in African childrenPathogens and Global Health, 1996
- Indicators of Life-Threatening Malaria in African ChildrenNew England Journal of Medicine, 1995
- Severe childhood malaria in two areas of markedly different falciparum transmission in East AfricaActa Tropica, 1994
- Beyond Chloroquine: Implications of Drug Resistance for Evaluating Malaria Therapy Efficacy and Treatment Policy in AfricaThe Journal of Infectious Diseases, 1993
- Seasonal variation of paediatric diseases in The Gambia, West AfricaPaediatrics and International Child Health, 1993
- Effect of blood transfusion on survival among children in a Kenyan hospitalThe Lancet, 1992
- Comparison of two simple methods for determining malaria parasite densityTransactions of the Royal Society of Tropical Medicine and Hygiene, 1991
- Prevention of transfusion-associated HIV transmission in Kinshasa, ZaireAIDS, 1990