Effects of Cholecystokinin on the Motility of the Distal Duodenum and the Proximal Jejunum in Man
- 1 May 1977
- journal article
- research article
- Published by Taylor & Francis in Scandinavian Journal of Gastroenterology
- Vol. 12 (3), 375-378
- https://doi.org/10.3109/00365527709180944
Abstract
Electrical spike potentials and intraluminal pressure variations were recorded in the distal part of the duodenum and proximal part of the jejunum in 5 normal human subjects before and after a bolus injection of cholecystokinin. A considerable increase in activity was observed in the jejunum after the hormone, whereas there was no response in the distal duodenum. Absence of reaction in the proximal duodenum and an increase in the motility in the distal ileum has previously been demonstrated after cholecystokinin administration. It is concluded that the human duodenum differs from the rest of the small intestine in its reaction to cholecystokinin. The change in reaction appears to occur on a level with the ligament of Treitz.Keywords
This publication has 10 references indexed in Scilit:
- Effects of Secretin and Cholecystokinin on Motor Activity of Human JejunumDigestion, 1975
- Quantitative analysis of motility recordings in the human small intestineDigestive Diseases and Sciences, 1974
- The effects of graded doses of C-terminal octapeptide of cholecystokinin on small intestinal transit time in manDigestive Diseases and Sciences, 1974
- A new disposable probe for recording intraluminal pressure and electric potentials in the human gastrointestinal tract.Gut, 1972
- Effect of Morphine, Cholecystokinin and Sympathomimetics on the Sphincter of Oddi and Intramural Pressure in Cat DuodenumScandinavian Journal of Gastroenterology, 1972
- Experiments with CholecystokininActa Radiologica, 1961