Radiation Treatment of Cancer of the Cervix of the Uterus at the Radium Institute in Copenhagen from 1951-54

Abstract

The methods used for calculation of survival fractions included the actuarial and the Boag lognormal prediction model methods in a study by Rabbe. A similar study comparing the estimates of the proportion of patients cured by the actuarial and Boag lognormal methods, for cervical carcinoma, was done. The results were based on patients treated from 1945-1959, with follow-up from 1969-1972, with each series being subdivided by stage and 5 yr treatment period: 1945-1949, 1950-1954 and 1955-1959. The minimum follow-up for the 1st quinquennium was 20 yr, compared with the 13 1/2 yr of the Rabbe data. Boag previously suggested that the model he set up is most useful as a framework for extrapolation from incomplete data to 10, 15 or 20 yr survival figures, rather than using C alone as a criterion. There is no difference between C and the actuarial estimate of long term survivors.