Fragment-Based QSAR and Molecular Modeling Studies on a Series of Discodermolide Analogs as Microtubule-Stabilizing Anticancer Agents
- 1 March 2009
- journal article
- research article
- Published by Wiley in QSAR & Combinatorial Science
- Vol. 28 (3), 325-337
- https://doi.org/10.1002/qsar.200860109
Abstract
No abstract availableKeywords
This publication has 43 references indexed in Scilit:
- Microtubule stabilizing agents: Their molecular signaling consequences and the potential for enhancement by drug combinationCancer Treatment Reviews, 2006
- Tubulin Assembly, Taxoid Site Binding, and Cellular Effects of the Microtubule-Stabilizing Agent DictyostatinBiochemistry, 2005
- Microtubules as a target for anticancer drugsNature Reviews Cancer, 2004
- Mechanisms of Taxol resistance related to microtubulesOncogene, 2003
- The spindle: a dynamic assembly of microtubules and motorsNature Cell Biology, 2001
- Tubulin as a target for anticancer drugs: Agents which interact with the mitotic spindleMedicinal Research Reviews, 1998
- THE DEVELOPMENT AND CLINICAL UTILITY OF THE TAXANE CLASS OF ANTIMICROTUBULE CHEMOTHERAPY AGENTSAnnual Review of Medicine, 1997
- Discodermolide, A Cytotoxic Marine Agent That Stabilizes Microtubules More Potently Than Taxol,Biochemistry, 1996
- Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations.Proceedings of the National Academy of Sciences, 1993
- Promotion of microtubule assembly in vitro by taxolNature, 1979