Pancreatic Islet-Acinar Cell Interaction: Amylase Messenger RNA Levels Are Determined By Insulin
- 17 July 1981
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 213 (4505), 351-353
- https://doi.org/10.1126/science.6166044
Abstract
Pancreatic amylase messenger RNA progressively decreases in rats rendered diabetic with streptozotocin. Insulin reverses this effect, inducing a selective decrease in amylase messenger RNA in the pancreas. Parotid amylase messenger RNA is not significantly affected by either diabetes or insulin.Keywords
This publication has 21 references indexed in Scilit:
- Structure of a family of rat amylase genesNature, 1980
- Isolation of biologically active ribonucleic acid from sources enriched in ribonucleaseBiochemistry, 1979
- Glucose activation of liver glycogen synthase. Insulin-mediated restoration of glucose effect in diabetic rate is blocked by protein synthesis inhibitorBiochimica et Biophysica Acta (BBA) - General Subjects, 1979
- The effect of residual insulin secretion on exocrine pancreatic function in juvenile-onset diabetes mellitusDiabetologia, 1978
- Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase IJournal of Molecular Biology, 1977
- Exocrine pancreatic function in juvenile diabeticsDigestive Diseases and Sciences, 1975
- Effects of Nutritional State and of Administration of Glucose, Glibenclamide or Diazoxide on the Storage of Amylase in Mouse PancreasDigestion, 1974
- The Role of Insulin in the Regulation of α‐Amylase Synthesis in the Rat PancreasEuropean Journal of Clinical Investigation, 1972
- Action de la biosynthèse de l'amylase et de quelques autres enzymes du pancréas de ratBiochimica et Biophysica Acta (BBA) - General Subjects, 1968
- A membrane-filter technique for the detection of complementary DNABiochemical and Biophysical Research Communications, 1966