Radical Pancreatoduodenectomy for Cancer of the Papilla of Vater
- 1 April 1977
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Surgery
- Vol. 112 (4), 451-456
- https://doi.org/10.1001/archsurg.1977.01370040103016
Abstract
• Over a 22-year span, 87 patients with carcinoma of the papilla of Vater underwent radical pancreatoduodenectomy. No patient was lost to follow-up, and extended observation was possible in most cases: the definitive operation was at least five years earlier than this study in 87% and at least ten years earlier in 73%. Operative mortality was 11.5% among patients who had a single definitive operative procedure and 15.4% among those whose treatment involved reoperation after prior exploration elsewhere. Overall survival rates at two, five, and ten years were 56%, 34%, and 20%, respectively. Factors associated with favorable survival were histologic differentiation (Broders grades 1 and 2), absence of nodal metastasis, and papillary histologic characteristics. Noteworthy is the fact that no patient having resection of an undifferentiated carcinoma (Broders grade 3 or 4) survived four years. (Arch Surg 112:451-456. 1977)Keywords
This publication has 2 references indexed in Scilit:
- Pancreatoduodenectomy for Periampullary CancerSurgical Clinics of North America, 1967
- Radical Resection of the Head of the Pancreas and of the Duodenum for Malignant Lesions: Some Factors in Operative Technique and Preoperative and Postoperative Care, with an Analysis of 85 CasesSurgical Clinics of North America, 1957