Generation of inhibitor-sensitive protein tyrosine phosphatases via active-site mutations
- 31 July 2007
- Vol. 42 (3), 278-288
- https://doi.org/10.1016/j.ymeth.2007.02.005
Abstract
No abstract availableKeywords
This publication has 46 references indexed in Scilit:
- Protein tyrosine phosphatases: from genes, to function, to diseaseNature Reviews Molecular Cell Biology, 2006
- MAPK-specific tyrosine phosphatases: new targets for drug discovery?Trends in Pharmacological Sciences, 2006
- A gatekeeper residue for inhibitor sensitization of protein tyrosine phosphatasesBioorganic & Medicinal Chemistry Letters, 2006
- Structure of the Hematopoietic Tyrosine Phosphatase (HePTP) Catalytic Domain: Structure of a KIM Phosphatase with Phosphate Bound at the Active SiteJournal of Molecular Biology, 2005
- Small molecule approach to studying protein tyrosine phosphataseMethods, 2005
- Protein Tyrosine Phosphatases in the Human GenomeCell, 2004
- Mutational Analysis of the Tyrosine Phosphatome in Colorectal CancersScience, 2004
- Cellular Effects of Small Molecule PTP1B Inhibitors on Insulin SignalingBiochemistry, 2003
- A novel strategy for the development of selective active-site inhibitors of the protein tyrosine phosphatase-like proteins islet-cell antigen 512 (IA-2) and phogrin (IA-2beta)Biochemical Journal, 2003
- Crystal structure of PTP-SL/PTPBR7 catalytic domain: implications for map kinase regulation 1 1Edited by D. ReesJournal of Molecular Biology, 2001