Antigen receptor‐mediated calcium signals in B cells as revealed by confocal fluorescence microscopy
- 24 June 1991
- journal article
- Published by Wiley in FEBS Letters
- Vol. 284 (2), 249-251
- https://doi.org/10.1016/0014-5793(91)80696-z
Abstract
A confocal fluorescence microscope was used to study the antigen receptor-mediated calcium signals in B cells. Anti-IgD binding to B lymphoma cells (BAL17) increased the intracellular calcium concentration with short lag times. Confocal fluorescence images of the fluo-3-loaded BAL17 cells showed that the intracellular calcium ion concentrations increased non-homogeneously, suggesting that the calcium signals transferred not only to the cytoplasm but also to the nucleus.Keywords
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