Effect of Desoxycorticosterone on the Colon: Its Relation to the Action of Cation Exchange Resins in Man.

Abstract

The present data indicate that the action of DOCA is not limited to a control of the transfer of sodium from the lumen of the kidney tubule to the surrounding blood stream but also influences the transfer of sodium from the lumen of the intestine to the surrounding blood stream. DOCA, in addition, influences the transfer of sodium through the sweat and salivary glands by decreasing the sodium concentrations in their secretions (13,14). The evidence indicates that DOCA affects the transfer of sodium through various organs, among them the colon, in each instance limiting the escape of sodium from the body.