Blunted Prefrontal Cortical 18Fluorodeoxyglucose Positron Emission Tomography Response to Meta-Chlorophenylpiperazine in Impulsive Aggression

Abstract

ALTHOUGH VIOLENT crime has decreased in the past decade, violent incidents involving impulsive aggression rather than planned violence are increasing.¹ These include juvenile violence, domestic violence, and workplace acts of aggression.^2,3 Violence and homicide are significantly associated with mental illness, especially antisocial and borderline personality disorder.⁴ Considering the serious consequences of impulsive-aggressive behavior, its neurobiology has received little scrutiny.