Abstract
Dr. Whisnant argues persuasively that control of hypertension has played a major role in the decline of stroke. He offers a cohesive and logical overview on this decline and does so with data from his own vast experience and with the advantages of the Mayo Clinic system which includes a centralized population-based diagnostic index, neurological expertise and a high autopsy rate. However, neither Dr. Whisnant's arguments nor the Mayo Clinic data justify the conclusion that "treatment of hypertension is the only significant contributor to the decline of stroke."