FURTHER STUDIES ON TULAREMIA IN THE OZARKS

Abstract

In 1948 Bost, Percefull, and Leming¹ published a paper reviewing 54 cases of tularemia seen at this hospital, half of whom had been seen before streptomycin was available and half of whom had been treated with this antibiotic. The present paper is a study of 44 additional patients treated at this hospital during a three year period ending Dec. 31, 1950. A report of these cases may seem unimportant per se, but we feel that the ineffectiveness of aureomycin that we encountered should be brought to the attention of the medical profession. Foshay,² who with Pasternack³ first reported the successful clinical use of streptomycin in tularemia, has recently recommended streptomycin and dihydrostreptomycin as the drugs of choice, but he states that aureomycin appears to have been effective in a few cases of averages severity. He adds that chloramphenicol (chloromycetin®) has been used experimentally and gives good indication