Leptin as a novel profibrogenic cytokine in hepatic stellate cells: mitogenesis and inhibition of apoptosis mediated by extracellular regulated kinase (Erk) and Akt phosphorylation
Open Access
- 2 August 2004
- journal article
- fj express-summary
- Published by Wiley in The FASEB Journal
- Vol. 18 (13), 1612-1614
- https://doi.org/10.1096/fj.04-1847fje
Abstract
A key feature in the molecular pathogenesis of liver fibrosis requires maintenance of the activated hepatic stellate cell (HSC) phenotype by both proliferation and inhibition of apoptosis. We provide...Keywords
Funding Information
- National Institutes of Health (AA 12933, DK 062092)
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