The Preparation of Specific Immune Sera against Type 3 Poliovirus D-Antigen and C-Antigen and the Demonstration of Two C-Antigenic Components in Vaccine Strain Populations

Abstract

Animals were immunized with purified D-antigen or C-antigen of type 3 poliovirus to produce specific antisera which were used to analyse the antigenic characteristics of the progeny virus in harvests from poliovirus type 3-infected cells.