Effects of indomethacin on bone ingrowth
- 1 January 1989
- journal article
- research article
- Published by Wiley in Journal of Orthopaedic Research
- Vol. 7 (1), 28-34
- https://doi.org/10.1002/jor.1100070105
Abstract
The effects of indomethacin, a nonsteriodal antiinflammatory agent, on bone ingrowth were studied using a rabbit animal model and a porous cylindrical implant system. Bone ingrowth was found to be independent of pore size in the range tested (0.6–1.0 mm). In the control (placebo‐treated) group, there was a significant increase in bone ingrowth between the 2‐ and 8‐week groups of animals. However, in the indomethacin‐treated group, there was no increase in bone ingrowth with time.Keywords
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