Abstract
Summary Hyaluronidase inhibitor in the blood serum of the rabbit was found to undergo no consistent change in concentration as the result of anaphylaxis induced by egg white. An elevation of the inhibitor level was observed during the acute phase of infection by Herpes simplex virus administered via the corneal route. Anaphylactic shock in rabbits which had recovered from the herpetic infection, administered via the leg route, resulted in elevated inhibitor values which were correlated with the severity of the disease thus precipitated from the latent state by the shock.